2009.09—2013.06 河海大学,材料科学与工程,获工学学士学位。
2013.09—2018.06 中国科学院上海硅酸盐研究所,材料学,获工学博士学位。
2018.07—2021.01 中国科学院大学宁波华美医院,助理研究员。
2018.09—2020.11 中国科学院宁波材料技术与工程研究所,博士后。
2021.02—2021.06 中国科学院宁波材料技术与工程研究所,客聘助理研究员。
2021.07—至今 中国科学院宁波材料技术与工程研究所,副研究员。
主要从事纳米生物材料在细菌感染疾病诊疗中的应用研究。近5年,共发表学术论文14篇,其中以第一作者/共同第一作者发表论文8篇;参编英文著作2本;申请国家发明专利5项(授权2项);作为项目负责人主持国家自然科学基金青年科学基金项目、浙江省自然科学基金探索项目、浙江省博士后择优资助、宁波市自然科学基金各1项,作为核心骨干参与宁波市“3315计划”C类创新团队和宁波市“科技创新2025”重大专项各1项。
研究方向:细菌靶向纳米材料、抗菌材料
联系方式:电话:0574-86685513,E-mail:xuchen@nimte.ac.cn
近5年主要论文:
- Chen Xu, Zihou Li, Ozioma Udochukwu Akakuru, Chunshu Pan, Ruifen Zou, Jianjun Zheng*, Aiguo Wu*. Maltodextrin-conjugated Gd-based MRI contrast agents for specific diagnosis of bacterial infections. ACS Applied Bio Materials, 2021, 4, 5, 3762–3772.
- Ozioma U. Akakuru, Chen Xu, Chuang Liu, Zihou Li, Jie Xing, Chunshu Pan, Yanying Li, Elvis I. Nosike, Zhoujing Zhang, Zubair M. Iqbal*, Jianjun Zheng*, and Aiguo Wu* Metal-free organo-theranostic nanosystem with high nitroxide stability and loading for image-guided targeted tumor therapy. ACS Nano, 2021, 15, 2, 3079–3097.
- Chunshu Pan, Junjie Lin, Jianjun Zheng, Chuang Liu, Bo Yuan, Ozioma Udochukwu Akakuru, M Zubair Iqbal, Qianlan Fang, Jiapeng Hu, Jia Chen, Jie Lin, Qi Dai, Xiuyu Guo, Zihou Li, Tao Zhang, Chen Xu, Xuehua Ma, Tianxiang Chen*, Aiguo Wu*, Yinhua Jin*. An intelligent T1–T2 switchable MRI contrast agent for the non-invasive identification of vulnerable atherosclerotic plaques. Nanoscale, 2021, 13, 6461-6474.
- Chen Xu, Ozioma Udochukwu Akakuru, Xuehua Ma, Jianping Zheng*, Jianjun Zheng*, Aiguo Wu*. Nanoparticle-based wound dressing: recent progress in the detection and therapy of bacterial infections. Bioconjugate Chemistry, 2020; 31(7): 1708-1723.
- Chen Xu, Ozioma Udochukwu Akakuru, Jianjun Zheng* and Aiguo Wu*, Applications of iron oxide-based magnetic nanoparticles in the diagnosis and treatment of bacterial infections. Frontiers in Bioengineering and Biotechnology, 2019, 7:141.
- Chen Xu, Bing Ma, Jinliang Peng, Long Gao, Yuhong Xu, Zhiguang Huan* and Jiang Chang*, Tricalcium silicate/graphene oxide bone cement with photothermal properties for tumor ablation. Journal of Materials Chemistry B, 2019,7, 2808~2818.
- Long Gao, Yanling Zhou, Jinliang Peng, Chen Xu, Qing Xu, Min Xing, Jiang Chang*. A novel dual-adhesive and bioactive hydrogel activated by bioglass for wound healing. NPG Asia Materials, 2019, 11(1): 1-11.
- Tiantian Wu#, Chen Xu#, Rong Du, Yang Wen, Jiang Chang, Zhiguang Huan*, Yaqin Zhu*, Effects of silicate-based composite material on the proliferation and mineralization behaviors of human dental pulp cells: An in vitro assessment. Dental Materials Journal, 2018, 37(6): 889~896.
- Yanling Zhou#, Chen Xu#, Xiaoya Wang, Yuandong Dou, Zhiguang Huan*, Jiang Chang*, Fast setting tricalcium silicate/magnesium phosphate premixed cement for root canal filling. Ceramics International, 2018, 44(3): 3015~3023.
- Chen Xu#, Xiaoya Wang, Jie Zhou, Zhiguang Huan*, Jiang Chang*, Bioactive tricalcium silicate/alginate composite bone cements with enhanced physicochemical properties. Journal of Biomedical Materials Research Part B-Applied Biomaterials, 2018, 106(1): 237~244.
- Chen Xu#, Yang Wen#, Yanling Zhou, Yaqin Zhu, Yuandong Dou, Zhiguang Huan*, Jiang Chang*, In vitro self-setting properties, bioactivity, and antibacterial ability of a silicate-based premixed bone cement. International Journal of Applied Ceramic Technology, 2018, 15(2): 460~471.
- Bing Ma#, Zhiguang Huan#, Chen Xu, Nan Ma, Haibo Zhu, Jipin Zhong, Jiang Chang*, Preparation and in vivo evaluation of a silicate-based composite bone cement. Journal of Biomaterials Applications, 2017, 32(2): 257~264.
- Zhiguang Huan, Chen Xu, Bing Ma, Jie Zhou*, Jiang Chang*, Substantial enhancement of corrosion resistance and bioactivity of magnesium by incorporating calcium silicate particles. RSC Advances, 2016, 6(53): 47897~47906.
专利:
- 中国发明专利,常江,徐晨,郇志广,一种抗溃散钙硅基复合骨水泥及其制备方法和应用,授权,2019.11.19,ZL201510797255.X
- 中国发明专利,常江,徐晨,郇志广,一种具有光热效应的钙硅基复合骨水泥及其制备方法和应用,授权,2021.04.16,ZL201810517797.0
- 中国发明专利,徐晨,郑建军,吴爱国,靶向革兰氏阳性细菌的磁共振成像造影剂、制备和应用,申请,2020.03.30,202010236129.8
- 中国发明专利,任文智,吴爱国,徐晨,一种经过还原的金属氧化物半导体纳米材料在抗菌材料中的应用,申请,2020.06.09,202010514520.X
- 中国发明专利,徐晨,郑建军,吴爱国,一种广谱细菌靶向型磁共振成像造影剂及其制备方法和应用,申请,2020.11.09,202011237671.1
主持和参与项目:
- 国家自然科学基金青年科学基金项目,2021.01.01—2023.12.31,在研,项目负责人
- 宁波市“科技创新2025”重大专项,2020.07.01—2023.06.30,在研,项目骨干
- 浙江省自然科学基金探索项目Q,2020.01.01—2022.12.31,在研,项目负责人
- 宁波市“3315计划”C类创新团队,2020.01.01—2024.12.31,在研,项目骨干
- 宁波市自然科学基金,2019.06.01—2021.05.31,结题,项目负责人
- 浙江省博士后择优资助,2019.06.01—2020.10.31,结题,项目负责人