吴爱国
中国科学院宁波材料技术与工程研究所研究员，博士生导师，党委委员，所学术委员会副主任，先进诊疗材料与技术实验室主任。江西南昌人，中共党员。
个人教育与研究经历:
1994-1998年 南昌大学化学系 本科 (优秀毕业生)
1998-2003年 中科院长春应化所-电分析化学国家重点实验室理学博士
指导老师 汪尔康院士／李壮研究员（获中科院彭荫刚奖学金）
2004-2005年 德国马尔堡大学 博士后（Norbert A Hampp教授课题组）
2005-2006年 美国加州理工学院 博士后（1999年诺贝尔化学奖获得者Ahmed H. Zewail教授课题组）
2006-2009年 美国西北大学医学院 助理研究员h（Gayle E. Woloschak教授课题组）
2009-2018年 中国科学院宁波材料技术与工程研究所 纳米事业部 研究员 (独立团队负责人)
2019-至 今 中国科学院宁波材料技术与工程研究所 先进诊疗材料与技术实验室 主任
个人主要荣誉:
国际生物材料科学与工程学会联合会会士(FBSE),
英国皇家化学会会士(FRSC),
英国皇家生物学会会士(FRSB),
中国生物材料学会理事,
中国生物材料学会：影像材料分会常委、科普专业委员会委员、
生物复合材料及医学转化分会常委、生物医用高分子分会委员、再生医学材料分会委员,
中国生物物理学会材料生物学与智能诊疗技术分会 副主任委员,
中国抗癌协会纳米肿瘤学专业委员会 副主任委员,
中国超声医学工程学会超声分子影像专业委员会 副主任委员,
中国生物医学工程学会纳米生物医学工程学分会 副主任委员,
国化学会分析化学学科委员会委员,
中科院人才 2010年入选，2011年获择优支持，
浙江省杰出青年基金 (2011，结题优秀)/省QR计划（2012），
中国分析测试学会科学技术特等奖(2014，2/10),
宁波市科学技术奖一等奖(2016，1/7),
美国西北大学医学院 Adjunct Professor 2013-2016,
德国马尔堡大学 访问教授 2015.01-2016.01,
中国科学院宁波材料技术与工程研究所 所长特别奖(首次) 团队负责人 2017,
Nano Research杂志纳米生物科技领域全球Young Innovator Awards获奖者 2018，
宁波市突出贡献专家 2019，
国家自然基金杰出青年基金 2020。
个人学术业绩:
吴爱国，研究员、国家级人才、中科院人才，国际生物材料科学与工程学会联合会会士(FBSE)，英国皇家生物学会会士(FRSB)，英国皇家化学会会士(FRSC)。现任中科院宁波材料所学术委员会副主任、中国生物材料学会理事、中国生物物理学会材料生物学与智能诊疗技术分会、中国抗癌协会纳米肿瘤学专业委员会、中国超声医学工程学会超声分子影像专业委员会及中国生物医学工程学会纳米生物医学工程学分会等4个副主任委员及中国化学会分析化学学科委员会委员等。
专注于分子影像探针生物材料及其相关仪器设备研究，在MRI探针材料、超声造影成像探针材料及NPY靶向的肿瘤治疗可视化成像探针材料和仪器开发等方面形成了独创性的研究体系做出了系统性贡献，先后在Adv Mater、Nano Lett、ACS Nano、Biomaterials及Chem Soc Rev等发表通讯（含共同）文章300余篇，被引用超2万次，获Nano Research杂志首届全球Nanobiotech青年创新奖(2018)等、中国分析测试学会科学技术奖励特等奖及宁波市科学技术一等奖等，出版专著4部（Wiley和中国科学出版社等）。获得中欧美专利112件（含美欧4件），牵头制定国家和团体标准各1项。
联系方式：电话：0574-86685039 E-mail：aiguo@nimte.ac.cn
主要论文
1. Xiawei Xu, Jie Lin*, Yanhong Guo, Xiaoxia Wu, Yanping Xu, Dinghu Zhang, Xiangzhi Zhang, Xie Yujiao, Jing Wang, Chengyang Yao, Junlie Yao, Jie Xing, Yi Cao, Yanying Li, Wenzhi Ren, Tianxiang Chen, Yong Ren*, Aiguo Wu*, TiO2-based Surface-Enhanced Raman Scattering bio-probe for efficient circulating tumor cell detection on microfilter, Biosensors and Bioelectronics,2022,210,114305.
2. Yanying Li, Yuanbo Pan, Yinjie Wang, Zhenqi Jiang, Ozioma U. Akakuru, Mingli Li, Xianyun Zhang, Bo Yuan, Jie Xing, Lijia Luo, Dan Larhammar, Aiguo Wu, Juan Li*, A D-peptide ligand of neuropeptide Y receptor Y1 serves as nanocarrier traversing of the blood brain barrier and targets glioma,Nano Today ,2022,44,101465.
3. Ting Dai#, Wenming He#, Shuangshuang Tu, Jinru Han, Bo Yuan, Chenyang Yao, Wenzhi Ren*, Aiguo Wu*, Black TiO2 nanoprobe-mediated mild phototherapy reduces intracellular lipid levels in atherosclerotic foam cells via cholesterol regulation pathways instead of apoptosis,Bioactive Materials,2022,17,18-28.
4. Yuanbo Pana#, Canxin Xub#, Hongzhang Deng, Qing You, Chenyang Zhao, Yanying Li, Qianqian Gao, Ozioma Udochukwu Akakuru, Juan Li*, Jianmin Zhang*, Aiguo Wu*, Xiaoyuan Chen*, Localized NIR-II laser mediated chemodynamic therapy of glioblastoma,Nano Today,2022,43,101435.
5. Chen Dong#, Mingsheng Xu#, Shuna Wang#, Menghui Ma, Ozioma U. Akakuru, Haizhen Ding, Aiguo Wu*, Zhengbao Zha*, Xuemei Wang, Hong Bi*, Fluorescent carbon dots with excellent moisture retention capability for moisturizing lipstick,Journal of Nanobiotechnology,2021,19,299.
6. Lin Huang#, Jie Feng#, Wenpei Fan*, Wei Tang, Xiaoxiang Rong, Wangjun Liao, Zhenni Wei, Yikai Xu, Aiguo Wu*, Xiaoyuan Chen*, Zheyu Shen*, Intelligent Pore Switch of Hollow Mesoporous Organosilica Nanoparticles for High Contrast Magnetic Resonance Imaging and Tumor-Specific Chemotherapy,Nano Letters,2021,21,9551−9559.
7. Yuanwei Pan, Xuehua Ma, Chuang Liu, Jie Xing, Suqiong Zhou, Badri Parshad, Tanja Schwerdtle,Wenzhong Li*, Aiguo Wu*, Rainer Haag*,Retinoic Acid-Loaded Dendritic Polyglycerol-Conjugated Gold Nanostars for Targeted Photothermal Therapy in Breast Cancer Stem Cells,ACS Nano,2021,15,15069-15084.
8. Chuang Liu, Shan Sun, Qiang Feng, Gongwei Wu, Yiting Wu, Na Kong, Zhangsen Yu, Junlie Yao, Xingcai Zhang, Wei Chen, Zhongmin Tang, Yufen Xiao, Xiangang Huang,Aman Lv, Chenyang Yao, Haibo Cheng, Aiguo Wu*, Tian Xie*, Wei Tao*,Arsenene Nanodots with Selective Killing Effects and their Low-Dose Combination with ß-Elemene for Cancer Therapy,Advanced Materials,2021,33,2102054.
9. Chen Dong, Shuna Wang, Menghui Ma, Peifa Wei, Yan Chen, Aiguo Wu∗, Zhengbao Zha*, Hong Bi*, Inhibition of oxidative stress in vivo through enzyme-like activity of carbon dots,Applied Materials Today,2021,25,101178.
10. Zhenqi Jiang, Xiao Han, Yang Du, Yanying Li, Yong Li, Juan Li*, Jie Tian*, Aiguo Wu*, Mixed Metal Metal−Organic Frameworks Derived Carbon Supporting ZnFe2O4/C for High-Performance Magnetic Particle Imaging,Nano Letters,2021,21,2730-2737.
11. Yuanbo Pan#, Canxin Xu#, Hongzhang Deng, Qing You, Chenyang Zhao, Yanying Li, Qianqian Gao, Ozioma Udochukwu Akakuru, Juan Li*, Jianmin Zhang*, Aiguo Wu*, Xiaoyuan Chen*, Localized NIR-II laser mediated chemodynamic therapy of glioblastoma, Nano Today,2022,43,101435.
12. Zhenqi Jiang#, Yanying Li#, Zhenni Wei, Bo Yuan,Yinjie Wang, Ozioma Udochukwu Akakuru,Yong Li, Juan Li*, Aiguo Wu*,Pressure-induced amorphous zeolitic imidazole frameworks with reduced toxicity and increased tumor accumulation improves therapeutic efficacy In vivo,Bioactive Materials,2021,6,740-748.
13.Chenyang Yao#, Fang Yang# *, Li Sun#, Yuanyuan Ma, Stefan G. Stanciu, Zihou Li, Chuang Liu, Ozioma Udochukwu Akakuru, Lipeng Xu, Norbert Hampp, Huanming Lu, Aiguo Wu*, Magnetically switchable mechano-chemotherapy for enhancing the death of tumour cells by overcoming drug-resistance,Nano Today,2020,35,100967.
14. Zhenqi Jiang, Bo Yuan, Yinjie Wang, Zhenni Wei, Shan Sun, Ozioma Udochukwu Akakuru, Yong Li, Juan Li∗, Aiguo Wu*, Near-infrared heptamethine cyanine dye-based nanoscale coordination polymers with intrinsic nucleus-targeting for low temperature photothermal therapy,Nano Today,2020,34,100910.
15. Shan Sun, Qiao Chen, Zhongdi Tang, Chuang Liu, Zhongjun Li, Aiguo Wu, Hengwei Lin*, Tumor Microenvironment Stimuli-Responsive Carbon Dots-Cu2+ Nanoassmeblies for Synergistic Cancer Therapy,Angew Chem Int Ed,2020,59,1041–21048.
16. Chuang Liu#, Junlie Yao#, Jiapeng Hu, Ozioma Udochukwu Akakuru#, Shan Sun, Tianxiang Chen*, Aiquo Wu*, Navigating nmof-mediated enzymatic reactionsfor catalytic tumor-specific therapy,Materials Horizons,2020,7,3176-3186.
17. Ozioma Udochukwu Akakuru, Chuang Liu, M. Zubair Iqbal*, Gohar Ijaz Dar, Gao Yang, Kun Qian, Elvis Ikechukwu Nosike, Jie Xing, Zhoujing Zhang, Yanying Li, Juan Li*, Aiguo Wu*, A hybrid organo-nanotheranostic platform of superlative biocompatibility for near-infrared-triggered fluorescence imaging and synergistically enhanced ablation of tumor, Small,2020,16,2002445.
18. Zhenni Wei, Zhenqi Jiang, Chunshu Pan, Jianbi Xia, Kaiwei Xu, Ting Xue, Bo Yuan, Ozioma Udochukwu Akakuru, Chengjie Zhu,Guilong Zhang, Zheng Mao, Xiaozhong Qiu *, Aiguo Wu*, Zheyu Shen *,Ten-Gram-Scale Facile Synthesis of Organogadolinium Complex Nanoparticles for Tumor Diagnosis,Small,2020,16,1906870.
19. Zheyu Shen, Ting Liu, Zhen Yang, Zijian Zhou, Wei Tang, Wenpei Fan*, Yijing Liu, Jing Mu, Ling Li, Vladimir I Bregadze, Swadhin K Mandal, Anna A Druzina, Zhenni Wei, Xiaozhong Qiu*, Aiguo Wu*, Xiaoyuan Chen*, Small-sized gadolinium oxidebased nanoparticles for high-efficiency theranostics of orthotopic glioblastoma, Biomaterials,2020,235,119783.
20. Xiaoyuan Zhang#, Coucong Gong#, Ozioma Udochukwu Akakuru, Zhiqiang Su*, Aiguo Wu*, The design and biomedical applications of self-assembled two-dimensional organic biomaterials,Chem Soc Rev,2019,48,5564-5595.
21. Jiang Zhenqi#, Yuan Bo#, Qiu Nianxiang, Wang Yinjie, Sun Li, Li Yanyin, Li Yong, Du Shiyu, Li Juan, Wu Aiguo*, Manganese-Zeolitic Imidazolate Frameworks-90 with High Blood Circulation Stability for MRI-Guided Tumor Therapy,Nano-Micro Letters,2019,11,61.
20. Zheyu Shen, Wenpei Fan*, Zhen Yang, Yijing Liu, Vladimir I. Bregadze, Swadhin K. Mandal, Bryant C. Yung, Lisen Lin, Ting Liu*, Wei Tang, Lingling Shan, Yuan Liu, Shoujun Zhu, Sheng Wang, Weijing Yang, L. Henry Bryant, Duong T. Nguyen, Aiguo Wu*, Xiaoyuan Chen*, Exceedingly Small Gadolinium Oxide Nanoparticles with Remarkable Relaxivities for Magnetic Resonance Imaging of Tumors, Small,2019,15,1903422.
21. Chuang Liu, Jie Xing, Ozioma Udochukwu Akakuru, Lijia Luo, Shan Sun, Ruifen Zou, Zhangsen Yu, Qianlan Fang, Aiguo Wu*, Nanozymes-Engineered Metal-Organic Frameworks for Catalytic Cascades-Enhanced Synergistic Cancer Therapy,Nano Letters,2019,19,5674-5682.
22. Lijia Luo, Muhammad Zubair Iqbal, Chuang Liu, Jie Xing, Ozioma Udochukwu Akakurua, Qianlan Fanga, Zihou Li, Yunlu Dai, Aiguo Li, Yong Guan, Aiguo Wu*, Engineered nano-immunopotentiators efficiently promote cancer immunotherapy for inhibiting and preventing lung metastasis of melanoma, Biomaterials,2019,223,119464.
23. Zhenqi Jiang#, Yinjie Wang#, Li Sun, Bo Yuan, Yuchen Tian, Lingchao Xiang,Yanying Li, Yong Li, Juan Li∗, Aiguo Wu*,Dual ATP and pH responsive ZIF-90 nanosystem with favorable biocompatibility and facile post-modification improves therapeutic outcomes of triple negative breast cancer in vivo,Biomaterials,2019,197,41-50.
24. Zheyu Shen, Jibin Song, Zijian Zhou, Bryant C. Yung, Maria A. Aronova, Yan Li, Yunlu Dai, Wenpei Fan, Yijing Liu*, Zihou Li, Huimin Ruan, Richard D. Leapman, Lisen Lin, Gang Niu, Xiaoytianuan Chen*, Aiguo Wu*, Dotted Core-Shell Nanoparticles with Superhigh r1 and Very Low r2/r1 for T1-Weighted MRI of Tumors,Adv Mater,2018,30,1803163.
25. Zheyu Shen, Jibin Song, Bryant C. Yung, Zijian Zhou*, Aiguo Wu*, Xiaoyuan Chen*, Emerging Strategies of Cancer Therapy Based on Ferroptosis, Adv Mater,2018,30,1704007.
26. Qiuyu Gong#, Ruifen Zou#, Jie Xing, Lingchao Xiang, Renshuai Zhang, Aiguo Wu*, A Ultrasensitive Near-Infrared Fluorescent Probe Reveals Pyroglutamate Aminopeptidase 1 Can Be a New Inflammatory Cytokine,Advanced Science,2018,5,1700664.
27. Zheyu Shen,Ting Liu, Yan Li, Joseph Lau, Zhen Yang, Wenpei Fan, Zijian Zhou, Changrong Shi, Chaomin Ke, Vladimir I. Bregadze,Swadhin K. Mandal, Yijing Liu*,Zihou Li, Ting Xue, Guizhi Zhu, Jeeva Munasinghe, Gang Niu, Aiguo Wu*, Xiaoyuan Chen*,Fenton-Reaction-Acceleratable Magnetic Nanoparticles for Ferroptosis Therapy of Orthotopic Brain Tumors,ACS Nano,2018,12,11355-11365.
28. Chuang Liu, Lijia Luo, Leyong Zeng, Jie Xing, Yuanzhi Xia, Shan Sun, Luyun Zhang, ZheYu, Junlie Yao, Zhangsen Yu,Ozioma Udochukwu, Akakuru, Madiha Saeed, Aiguo Wu*,Porous gold nanoshells on functional NH2-MOFs: facile synthesis and designable platforms for cancer multiple therapy,Small,2018,14,1801851.
29. Yuanzhi Xia#, Xuehua Ma #, Junhua Gao, Guoxin Chen, Zihou Li, Xiaoxia Wu, Zhangsen Yu, Jie Xing, Li Sun, Huimin Ruan, Lijia Luo，Lingchao Xiang, Chen Dong, Wenzhi Ren, Zheyu Shen *, Aiguo Wu*, A Flexible Caterpillar-Like Gold Nanoparticle Assemblies with Ultra-Small Nanogaps for Enhanced Dual-Modal Imaging and Photothermal Therapy, Small,2018,14,1800094.
30. Zhenqi Jiang#, Yuchen Tian#, Dingying Shan, Yinjie Wang, Ethan Gerhard, Jianbi Xia, Rong Huang, Yan He, Aiguo Li, Jianchao Tang,Huimin Ruan, Yong Li, Juan Li*, Jian Yang, Aiguo Wu*,pH protective Y1 receptor ligand functionalized antiphagocytosis BPLP-WPU micelles for enhanced tumor imaging and therapy with prolonged survival time,Biomaterials,2018,170,70-81.
31. Bushra Tehseen, Asma Rehman*, Muniba Rahmat, Haq Nawaz Bhatti, Aiguo Wu, Faheem K. Butt, Gul Naz, Waheed S. Khan*, Sadia Z. Bajwa*, Solution growth of 3D MnO2 mesh comprising 1D nanofibres as a novel sensor for selective and sensitive detection of biomolecules, Biosensors and Bioelectronics,2018,117,852-859.
32. Zheyu Shen, Aiguo Wu*, Xiaoyuan Chen*, Current detection technologies for circulatingtumor cells,Chem Soc Rev,2017,46,2038-2056.
33. Zheyu Shen#, Tianxiang Chen#, Xuehua Ma, Wenzhi Ren, Zijian Zhou, Guizhi Zhu, Ariel Zhang, Yijing Liu, Jibin Song*, Zihou Li, Huimin Ruan, Wenpei Fan, Lisen Lin, Jeeva Munasinghe, Xiaoyuan Chen*, Aiguo Wu*, Multifunctional Theranostic Nanoparticles Based on Exceedingly Small Magnetic Iron Oxide Nanoparticles for T 1 ‑Weighted Magnetic Resonance Imaging and Chemotherapy,ACS Nano,2017,11,10992-11004.
34. Juan Li#, Yuchen Tian#, Dingying Shan, An Gong, Leyong Zeng, Wenzhi Ren, Lingchao Xiang, Ethan Gerhard, Jinshun Zhao, Jian Yang, Aiguo Wu*, Neuropeptide Y Y1 receptor-mediated biodegradable photoluminescent nanobubbles as ultrasound contrast agents fortargeted breast cancer imaging, Biomaterials,2017,116,106-117.
35. Leyong Zeng, Yuanwei Pan, Ruifen Zou, Jinchao Zhang, Ying Tian, Zhaogang Teng, Shouju Wang, Wenzhi Ren, Xueshan Xiao, Jichao Zhang, Lili Zhang, Aiguo Li, Guangming Lu*, Aiguo Wu*,808 nm-excited upconversion nanoprobes with low heating effect fortargeted magnetic resonance imaging and high-efficacyphotodynamic therapy in HER2-overexpressed breast cancer, Biomaterials,2016,103,116-127.
36. Lulu Pan, Shan Sun, Aidi Zhang, Kai Jiang, Ling Zhang, Chaoqing Dong, Qing Huang, Aiguo Wu*, Hengwei Lin*, Truly fluorescent excitation-dependent carbon dots and their applications in multicolor cellular imaging and multidimensional sensing,Adv Mater,2015,27,7782–7787.
37. Kai Jiang,Shan Sun, Ling Zhang, Yue Lu, Aiguo Wu*, Congzhong Cai, Hengwei Lin*,Red Green and Blue Luminescence by Carbon Dots: Full-Color Emission Tuning and Multicolor Cellular Imaging,Angew Chem Int Ed,2015,127(18),5450-5453.
38. Zheyu Shen, Hao Wu, Sugeun Yang, Xuehua Ma, Zihou Li, Mingqian Tan*, Aiguo Wu*, A novel Trojan-horse targeting strategy to reduce the non-specific uptake of nanocarriers by noncancerouscells, Biomaterials,2015,70,1-11.
39. Leyong Zeng, Yuanwei Pan, Ying Tian, Xin Wang, Wenzhi Ren, Shouju Wang, Guangming Lu*, Aiguo Wu*, Doxorubicin-loaded NaYF4: Yb/Tm-TiO2 inorganic photosensitizers for NIR-triggered photodynamic therapy and enhanced chemotherapy in drug-resistant breast cancers, Biomaterials,2015,57,93-106.
40. Ling'e Zhang, Leyong Zeng*, Yuanwei Pan, Song Luo, Wenzhi Ren, An Gong, Xuehua Ma, Hongze Liang, Guangming Lu*, Aiguo Wu*, Inorganic photosensitizer coupled Gd-based upconversionluminescent nanocomposites for in vivo magnetic resonance imagingand near-infrared-responsive photodynamic therapy in cancers, Biomaterials,2015,44,82-90.
41. Xuefeng Yan, Gang Niu, Jing Lin, Albert J. Jin, Hao Hu, Yuxia Tang, Yujie Zhang, Aiguo Wu*, Jie Lu, Shaoliang Zhang, Peng Huang*, Baozhong Shen*, Xiaoyuan Chen*, Enhanced fluorescence imaging guided photodynamic therapy ofsinoporphyrin sodium loaded graphene oxide, Biomaterials,2015,42,4294-4302.
42. Zhenzhi Shi, Wenzhi Ren, An Gong, Xinmei Zhao, Yuehong Zou,Eric Michael Bratsolias Brown, Xiaoyuan Chen, Aiguo Wu*,Stability enhanced polyelectrolyte-coated gold nanorod-photosensitizer complexes for high/low power density photodynamic therapy,Biomaterials,2014,35,7058-7067.
43. Christine A. Falaschetti, Tatjana Paunesku, Jasmina Kurepa, Dhaval Nanavati, Stanley S. Chou, Mrinmoy De, MinHa Song, Jung-tak Jang, Aiguo Wu*, Vinayak P. Dravid, Jinwoo Cheon, Jan Smalle, Gayle E. Woloschak*, Negatively Charged Metal Oxide Nanoparticles Interact with the 20S Proteasome and Differentially Modulate Its Biologic Functional Effects,ACS Nano,2013,7(9),7759-7772.
44. Kenneth T. Thurn, Tatjana Paunesku, Aiguo Wu*, Eric M. B. Brown, Barry Lai, Stefan Vogt, Jörg Maser, Mohammed Aslam, Vinayak Dravid, Raymond Bergan, Gayle E. Woloschak,Labeling TiO2 Nanoparticles with Dyes for Optical Fluorescence Microscopy and Determination of TiO2-DNA Nanoconjugate Stability,Small,2009,5(11),1318-1325.
申请专利：
(1) 纳米材料或微纳器件的显微重复定位方法。
发明人：吴爱国，曾乐勇。专利号：ZL200910152441.2
(2）利用ⅤA族或ⅥA族元素化合物检测金属阳离子的方法。
发明人：张付强，吴爱国，曾乐勇，崔平。专利号：ZL201010251278.8
(3) 一种Cd2+的检测方法。
发明人：吴爱国，苗利静，沈折玉，曾乐勇。专利号：ZL201210391120.X
(4) 一种核壳结构的复合纳米材料及其制法和应用。
发明人：曾乐勇，吴爱国。专利号：ZL201510405522.4
(5) 一种核磁共振快速检测金属离子与小分子化合物的方法。
发明人：吴爱国，陈宁怡，张玉杰。专利号：ZL201510107195.4
(6) 一种铋基复合纳米材料及其肿瘤诊断与治疗应用。
发明人：吴爱国，史振志，徐裕。专利号：ZL201410788424.9
(7) 一种新型造影材料、其制备方法及应用。
发明人：陈天翔，吴爱国。专利号：ZL201410430551.1
(8) 金属离子的检测方法。
发明人：张付强，吴爱国，曾乐勇。专利号：ZL201010194041.0
(9) 纳米粒子和纳米粒子溶胶的制备方法及两者在磁共振成像造影剂中的应用。
发明人：吴爱国，曾乐勇，崔平。专利号：ZL201010175917.7
(10) 一种高产率合成（200）晶面为主的纳米金棒的制备方法及应用。
发明人：冷玉敏，吴爱国，尹训君。专利号：ZL201110363934.8
(11) 一种铅离子的检测方法。
发明人：张玉杰，吴爱国。专利号：ZL201110299385.2
(12) Fe3O4复合TiO2纳米粒子及其制备方法以及在磁共振成像造影剂中的应用。
发明人：吴爱国，曾乐勇。专利号：ZL201010039632.0
(13) 一种制备不同形貌的银纳米粒子的绿色方法。
发明人：辛军委，吴爱国。专利号：ZL201110378232.7
(14) 水溶性具有核壳结构或核冕壳结构的材料的制备方法。
发明人：吴爱国，曾乐勇，张付强，崔平。专利号：ZL201110000844.2
(15) multifunction nanoconjugates for imaging applications and targeted treatment。
发明人：Ai Guo Wu，Tatjana Paunesku，Gayle E.Woloschak。专利号：US8557290B2
(16) 顺磁-上转换发光复合纳米粒子及其制备方法和应用。
发明人：曾乐勇，吴爱国，崔平。专利号：ZL201110032000.6
(17) 一种水溶性纳米复合材料及其制备方法和应用。
发明人：张颖鑫，吴爱国，聂秀青。专利号：ZL201110241124.5
(18) 一种六价铬离子的检测方法。
发明人：辛军委，吴爱国。专利号：ZL201110378260.9
(19) 主动靶向型小干扰核糖核酸输送载体及其制备方法。
发明人：沈折玉，吴爱国，任文智，马雪华。专利号：ZL201210475752.4
(20) 一种用于无机光动力治疗的复合纳米粒子及其制备方法。
发明人：曾乐勇，吴爱国。专利号：ZL201210172056.6
(21) 用于检测和吸附汞离子的双功能材料及其合成方法和应用。
发明人：吴爱国，汪竹青，赵新梅。专利号：ZL201210396580.1
(22) 肿瘤早期诊断用隐形造影材料及其制备方法。
发明人：沈折玉，吴爱国。专利号：ZL201210230833.8
(23) 一种快速检测溶液中铜离子的方法。
发明人：吴爱国，苗利静，辛军委。专利号：ZL201210097477.7
(24) Gd2O3-TiO2复合纳米粒子及其制备方法和应用。
发明人：吴爱国，马雪华，沈折玉。专利号：ZL201210539796.9
(25) 一种快速检测多种单一金属离子的检测试剂及其制备和应用。
发明人：吴爱国，冷玉敏。专利号：ZL201210159826.3
(26) 检测二价汞离子的检测组合物、方法与试剂盒。
发明人：吴爱国，高月霞，沈折玉。专利号：ZL201310091158.X
(27) 一种检测二价锰离子的方法。
发明人：吴爱国，高月霞，沈折玉。专利号：ZL201210310138.2
(28) 一种基于纳米粒子的肿瘤细胞主动靶向给药体系及其构建方法。
发明人：任文智，吴爱国。专利号：ZL201110397312.7
(29) 一种检测二价镍离子的方法。
发明人：吴爱国，杨宁宁，沈折玉。专利号：ZL201210341510.6
(30) 便携式食品安全检测试剂及其制备方法与应用。
发明人：吴爱国，冷玉敏，张玉杰。专利号：ZL201310511426.9
(31) 基于苯酚类有机分子为碳源的磁性MFe2O4/C/AOX的复合材料及其制备方法。
发明人：赵新梅，吴爱国。专利号：ZL201110334606.5
(32) 靶向型诊疗联用药物及其制备方法和应用。
发明人：沈折玉，吴爱国，马雪华，龚安，任文智，李娟。专利号：ZL201310318107.6
(33) 一种纳米金溶液及利用该纳米金溶液检测Co2+的方法。
发明人：冷玉敏，吴爱国。专利号：ZL201110363954.5
(34) 一种超声/荧光双模态微胶囊造影剂的制备方法。
发明人：吴爱国，龚安，沈折玉，马雪华，项灵超。专利号：ZL201310755481.2
(35) 一种基于苯胺类有机小分子为碳源的磁性MFe2O4/C/M′的制备方法 。
发明人：张颖鑫，吴爱国。专利号：ZL201110334595.0
(36) 一种半胱氨酸的检测试剂及检测方法。
发明人：吴爱国，李永龙，沈折玉。专利号：ZL201310367104.1
(37) 一种肿瘤治疗复合纳米材料及其制备。
发明人：任文智，吴爱国。专利号：ZL201410175018.5
(38) 一种造影材料、其制备方法及应用。
发明人：陈天翔，吴爱国，龚安。专利号：ZL201510465373.0
(39) 三元纳米复合药物、其制备方法和其用于制备治疗肿瘤的药学组合物的用途。
发明人：任文智，吴爱国，曾乐勇，沈折玉，马雪华。专利号：ZL201310103775.7
(40) 主动靶向型抗肿瘤药物及其制备方法。
发明人：李娟，吴爱国。专利号：ZL201310407938.0
(41) 一种三价铝离子检测试剂及检测方法。
发明人：吴爱国，杨宁宁，高月霞，张玉杰，沈折玉。专利号：ZL201310386230.1
(42) 一种样品输入/输出的联动装置 。
发明人：杨方，吴爱国，马园园。专利号：ZL201720764846.1
(43) 主动靶向型抗肿瘤药物及其制备方法。
发明人：李娟，吴爱国。专利号：CH710313B1
(44) 一种二价汞离子的检测试剂组合及检测方法。
发明人：吴爱国，李永龙，沈折玉。专利号：ZL201310382118.0
(45) 一种钼掺杂的纳米二氧化钛光催化剂的制备方法。
发明人：诸葛飞，李振超，吴爱国，曾乐勇，沈折玉，徐裕，梁凌燕，曹鸿涛。专利号：ZL201510468562.3
(46) 一种可见光响应的碳掺杂纳米二氧化钛催化剂的制备方法。
发明人：诸葛飞，卜彦强，李振超，梁凌燕，曹鸿涛，吴爱国，曾乐勇，沈折玉，徐裕。专利号：ZL201510771557.X
(47) 一种土壤重金属固定剂及其制备方法和应用。
发明人：吴爱国，刘弘禹，张玉杰。专利号：ZL201510511727.0
(48) 一种基于表面增强拉曼散射技术的复合材料及其制备方法。
发明人：沈折玉，吴爱国，武小侠，张玉杰，阮慧敏。专利号：ZL201610234754.2
(49) 主动靶向型抗脑肿瘤药物及其制备方法。
发明人：李娟，吴爱国，田宇辰。专利号：ZL201510535764.5
(50) 软镜保护套及其可视软镜。
发明人：漆勇，吴爱国，李娟，项灵超，蒋振奇。专利号：ZL201820551661.7
(51) 一种具有Janus 结构的复合纳米粒子及其制备方法和应用。
发明人：Muhammad Zubair Iqbal，吴爱国，曾乐勇，马雪华，陈天翔。专利号：ZL201510504659.5
(52) 一种磁性纳米粒子及其制备方法和应用。
发明人：吴爱国，陈天翔，马雪华，邹瑞芬，Muhammad Zubair Iqbal，项灵超。专利号：ZL201511005964.6
(53) 一种亲水性实心球形材料、制备方法及其应用。
发明人：杨方，吴爱国，孙莉。专利号：ZL201710447334.7
(54) 一种检测分析仪。
发明人：杨方，吴爱国，马园园。专利号：ZL201710508203.5
(55) 化合物、其制备方法及含有其的荧光探针和应用。
发明人：吴爱国，邢洁，龚秋雨，邹瑞芬。专利号：ZL201711170016.7
(56) 一种化合物、其制备方法及作为荧光探针的应用。
发明人：吴爱国，邹瑞芬，龚秋雨。专利号：ZL201711208547.0
(57) 一种纳米生物医用材料的生产系统及其生产方法。
发明人：王爱芳，李全，谷新春，王宇光，张志，郭仁君，吴卓娅，林建英，吴爱国，陈天翔，马雪华，任文智，李升大，孟启贵，卫维剑，李子英。专利号：ZL201811365454.3
(58) 一种纳米生物医用材料的生产系统及其生产工艺。
发明人：王爱芳，李全，谷新春，王宇光，张志，郭仁君，吴卓娅，林建英，吴爱国，陈天翔，马雪华，任文智，李升大，孟启贵，卫维剑，李子英。专利号：ZL201811365459.6
(59) 一种基于智能手机快速现场检测金属离子的方法。
发明人：吴爱国，董晨，沈折玉。专利号：ZL201510508573.X
(60) 一种抗癌药物复合物及其制备方法和应用。
发明人：李娟，蒋振奇，吴爱国，王胤杰，袁博，房倩兰，李彦莹。专利号：ZL201711209793.8
(61) 一种主动靶向型超声/荧光双模态造影剂及其制备方法和应用。
发明人：李娟，田宇辰，吴爱国。专利号：ZL201610235965.8
(62) 一种纳米复合材料、其制备方法及应用。
发明人：吴爱国，叶羽凡，邢洁。专利号：ZL201710145917.4
(63) 一种七甲川硝基吲哚花菁染料以及该染料的制备方法和用途。
发明人：吴爱国，蒋振奇，袁博，李娟。专利号：ZL201910175647.0
(64) 一种用于可代替用力肺活量检查上机前宣教的峰流装置。
发明人：倪霞，郎如意，李娟，吴爱国，项灵超。专利号：ZL202023063413.4
(65) 沸石咪唑框架结构材料的制备方法。
发明人：吴爱国，蒋振奇，李娟，王胤杰，袁博，项灵超，李彦莹。专利号：ZL201810007681.2
(66) 一种纳米复合材料、其制备方法及应用。
发明人：张涛，吴爱国，任文智，蒋振奇，薛婷，马雪华。专利号：ZL201810907829.8
(67) 一种新型土壤重金属固定剂及其制备方法和应用。
发明人：吴爱国，刘弘禹，张玉杰。专利号：ZL201610176022.2
(68) 一种碘离子吸附剂、其制备方法及应用。
发明人：吴爱国，孙犁，张玉杰，刘海宁，叶秀深，张慧芳，吴志坚。专利号：ZL201710155686.5
(69) 一种上转换荧光数字全息成像系统及数字全息成像方法。
发明人：吴爱国，俞樟森，杨方。专利号：ZL201711173737.3
(70) 一种二维纳米复合材料、其制备方法及其应用。
发明人：吴爱国，陈天翔，房倩兰。专利号：ZL201911411094.0
(71) 一种复合纳米材料、其制备方法及其应用。
发明人：陈天翔，吴爱国，马雪华，任文智。专利号：ZL201810468692.0
(72) 一种磁性复合纳米材料及其制备方法与应用。
发明人：沈折玉，钱昆，吴爱国。专利号：ZL202010160598.6
(73) 一种七甲川吲哚花菁染料的制备方法以及该染料的用途。
发明人：李娟，袁博，蒋振奇，吴爱国。专利号：ZL201910176083.2
出版专著：
1. Mingqian Tan*, Aiguo Wu*. “Nanomaterials for Tumor Targeting Theranostics”. World Scientific Publishing, Singapore. 2015. (ISBN: 978-981-4635-41-7).
2. Leyong Zeng, Zheyu Shen, Aiguo Wu*. Chapter 3: Magnetic Nanoparticles for Tumor Targeting Theranostics, pp53-80, Editors: Mingqian Tan*, Aiguo Wu*. “Nanomaterials for Tumor Targeting Theranostics”. World Scientific Publishing, Singapore. 2015. (ISBN: 978-981-4635-41-7).
3. Zhenzhi Shi, Yu Xu, Aiguo Wu* “Chapter III: Gold Nanorods for Biomedical Imaging and Therapy in Cancer”. pp 103-136, Editor: Zhifei Dai, Advances in Nanotheranostics I: Design and Fabrication of Theranostic Nanoparticles. Springer, 2016 (ISSN:2195-0644, ISSN2195-0652 (electronic)).
4. Muhammad Zubair Iqbal, Aiguo Wu* “Chapter V: Magnetic Nanohybrids for Magnetic Resonance Imaging and Phototherapy Applications”, pp101-150, Editor: Donglu Shi, Tissue Engineering and Nanotheranostics, World Scientific Publishing, Singapore. 2017.
5. 吴爱国，张玉杰。功能化材料及其环境应用，2019年4月出版，科学出版社，ISBN978-7-03-060222-0
6. M. Zubair Iqbal, Gohar Ijaz Dar, Israt Ali, and Aiguo Wu*. “Chapter 10: Magnetic
7. Nanomedicine.” pp 269-302, Editor: Xue Xue, Nanomedicine in Brain Diseases. Springer, Germany, 2019. (ISBN 978-981-13-8730-2, ISBN 978-981-13-8731-9 (eBook) )
8. Fang Yang*, Yuanyuan Ma, Stefan G. Stanciu, Aiguo Wu. “chapter-2: Transduction Process-Based Classification of Biosensors.” Editor: 9. Aiguo Wu*, Waheed S. Khan. Nanobiosensors：From Design to Applications. WILEY-VCH, Germany, 2020. (ISBN: 9783527345106)
9. Aiguo Wu, Wenzhi Ren. “TiO2 Nanoparticles: Applications in Nanobiotechnology and Nanomedicine”. WILEY-VCH, Germany, 2020. (ISBN：9783527347247)
10.Aiguo Wu, Waheed S. Khan. “Nanobiosensors：From Design to Applications”. WILEY-VCH, Germany, 2020. (ISBN: 9783527345106)
11. Li Sun, Aiguo Wu, Artificial Protein and Peptide Nanofibers: Design, Fabrication, Characterization, and Applications “Chapter 12: Nanofiber-based hydrogels and aerogels”. pp259-278, Editor: Gang Wei, Sangamesh G. Kumbar., Elsevier, Netherlands, 2020. (ISBN 978-0-08-102850-6/ 978-0-08-102851-3)
12. Jie Lin, Aiguo Wu, “Chapter 7: SERS methods based on nanomaterials as a diagnositic tool of cancer”. pp189-212, Editor: Suvardhan Kanchi, Deepali Sharma. Nanomaterials in Diagnostic Tools and Devices, Elsevier, Netherlands, 2020. (ISBN: 978-0-12-817923-9)
13. Elvis Ikechukwu Nosike, Yujie Zhang, Aiguo Wu, “Chapter 22: Magnetic hybrid nanoparticles for environmental remediation”. Pp591-616, Editor: Andrea Ehrmann, Tuan Anh Nguyen, Mazaher Ahmadi, Ali Farmani, Phuong Nguyen-Tri, Magnetic Nanoparticle-Based Hybrid Materials, Elsevier, Netherlands, 2021. (ISBN: 9780128236888/ 9780128236895)