2006/09-2010/07，Inner Monglia Argiculture University , Bachelor.
2010/09-2013/07，Ningbo Institute of Materials Technology &Engineering, Chinese Academy of Sciences, Master.
2013/07-2015/12，Division of Functional Materials and Nano Devices, Ningbo Institute of Material Technology &Engineering, Chinese Academy of Sciences, Research Assistant.
2016/01-Now，Division of Functional Materials and Nano Devices, Ningbo Institute of Material Technology &Engineering, Chinese Academy of Sciences, Engineer
Reseaerch Interests:
Fe/Gd based medical MRI contrast agents materials synthesis and application
Contact：Tel：+86-0574-86685513，E-mail：maxh@nimte.ac.cn
Main Publications：
1.Xuehua Ma, An Gong, Bin Chen, Jianjun Zheng, Tianxiang Chen, Zheyu Shen*, Aiguo Wu*, Exploring a new SPION-based MRI contrast agent with excellent water-dispersibility, high specificity to cancer cells and strong MR imaging efficacy, Colloids and Surfaces B: Biointerfaces, 2015, 126: 44-49.
2.Xuehua Ma, An Gong, Lingchao Xiang, Tianxiang Chen, Yuexia Gao, Xingjie Liang, Zheyu Shen*, Aiguo Wu*, Biocompatible composite nanoparticles with large longitudinal lrelaxivity for targeted imaging and early diagnosis of cancer, Journal of Materials Chemistry B, 2013, 1(27): 3419-3428.
3.Zheyu Shen, Hao Wu, Sugeun Yang, Xuehua Ma, Zihou Li, Mingqian Tan*, Aiguo Wu*, A novel Trojan-horse targeting strategy to reduce the non-specific uptake of nanocarriers by non-cancerous cells, Biomaterials, 2015, 70: 1-11.
4.Muhammad Zubair Iqbal, Xuehua Ma, Tianxiang Chen, Linge Zhang, Wenzhi Ren, Lingchao Xiang, Aiguo Wu*, Silica Coated Super-paramagnetic Iron Oxide Nanoparticles (SPIONPs): A New Type Contrast Agent of T1 Magnetic Resonance Imaging (MRI), Journal of materials chemistry B, 2015, 3(26): 5172-5181.
5.Xiaoxia Wu, Liqiang Luo, Sugeun Yang, Xuehua Ma, Yonglong Li, Chen Dong, Yuchen Tian, Ling'e Zhang, Zheyu Shen*, Aiguo Wu*, Improved SERS Nanoparticles for Direct Detection of Circulating Tumor Cells in the Blood, ACS Applied Materials & Interfaces, 2015, 7(18): 9965-9971.
6.Juan Li, Zheyu Shen, Xuehua Ma, Wenzhi Ren, Lingchao Xiang, An Gong, Tian Xia, Junming Guo, Aiguo Wu*, Neuropeptide Y Y1 Receptors Meditate Targeted Delivery of Anticancer Drug Encapsulating Nanoparticles to Breast Cancer Cells with High Selectivity and Its Potential for Breast Cancer Therapy, ACS Applied Materials & Interfaces, 2015, 7(9): 5574-5582.
7.Ling'e Zhang, Leyong Zeng*, Yuanwei Pan, Song Luo, Wenzhi Ren, An Gong, Xuehua Ma, Hongze Liang, Guangming Lu, Aiguo Wu*, Inorganic photosensitizer coupled Gd-based upconversion luminescent nanocomposites for in vivo magnetic resonance imaging and near-infrared-responsive photodynamic therapy in cancers, Biomaterials, 2015,44: 82-90.
8.An Gong, Xuehua Ma, Lingchao Xiang, Wenzhi Ren, Lingchao Xiang, Zheyu Shen*, AiguoWu*, Improved double emulsion technology for fabricating autofluorescent microcapsules as novel ultrasonic/fluorescent dual-modality contrast agents, Colloids and Surfaces B: Biointerfaces, 2014, 116: 561-567.
9.Wei Zhang, Bowei Li, Lingxin Chen*, Yunqing Wang, Dingxue Gao, Xuehua Ma, Aiguo Wu*, Brushing, a simple way to fabricate SERS active paper substrates, Analytical methods, 2014, 6(7): 2066-2071.
10.Shanmin Gao, Xin Liu, Tao Xu, Xuehua Ma, Zheyu Shen, Aiguo Wu, Yinghuai Zhu, Narayan S. Hosmane*, Synthesis and characterization of Fe10BO3/Fe3O4/SiO2 and GdFeO3/Fe3O4/SiO2: nanocomposites of biofunctional materials, Chemistry Open, 2013, 2(3): 88-92.
Patents：
1.Aiguo Wu, Xuehua Ma, Zheyu Shen; Gd2O3-TiO2 composite nanoparticles and the fabrication and application methods; Application date: 2012-12-12；Application number: 201210539796.9; Authorization date: 2014-11-26; Number of authorization notice: CN 103007302 B; Patent number: ZL201210539796.9; Authorized by: China.
2.Zheyu Shen, Aiguo Wu, Wenzhi Ren, Xuehua Ma；Actively targeted delivery vectors of siRNA and the fabrication method; Application Date: 2012-11-20; Application number: 2012104757524；Authorization date: 2014-06-18; Number of authorization notice: CN 102949727 B; Patent number: ZL201210475752.4; Authorized by: China.
3.Zheyu Shen, Aiguo Wu, Wenzhi Ren, Xuehua Ma；Actively targeted delivery vectors of siRNA and the fabrication method; International application Date: 2013-01-11; International application number: PCT/CN2013/070362; International publication date: 2014-05-30; International publication number: WO 2014/079158 A1. (PCT)
4.Zheyu Shen, Aiguo Wu, Xuehua Ma, An Gong, Wenzhi Ren, Juan Li；Targeting diagnostic and therapeutic drug and its preparation method and application；Application date: 2013-07-24; Application number:2013103181076；Authorization date: 2015-12-02; Number of authorization notice: CN 103446588 B; Patent number: ZL201310318107.6; Authorized by: China.
5.Aiguo Wu, An Gong, Zheyu She, Xuehua Ma, Lingchao Xiang；A fabrication method of an ultrasonic/fluorescent dual-modality microcapsule contrast agent. Application date: 2013-12-31; Application number: 201310755481.2; Patent number: ZL201310755481.2; Authorized by: China.
6.Muhammad Zubair lqbal, Aiguo Wu, Xuehua Ma; Preparation method and application of a kind of magnetic nanoparticles; Application Date:2014.05.15; Application number: 201410203774.4.
7.Muhammad Zubair lqbal, Aiguo Wu, Leyong Zeng, Xuehua Ma；Preparation method and application of a kind of Janus nanoparticles; Application Date: 2015.08.18; Application number:201510504659.5.